Located between Elizabeth and Swanston streets and extending south from Flinders Lane, Rothsay Lane was named pre-1915 after the Duke of Rothsay Hotel which was situated adjacent.
On 7 March 1891, decorator and sign writer W. Brettschneider, who operated his business from 266 Flinders Street, complained of an 'unbearable stench arising from putrid offal' that was stored at the rear of his premises by a neighbouring restaurant keeper. In May 1893, a similar complaint was received from Tebbut, Brice and Frecknell who were listed as 'Manufacturers, Importers and General Indentors' and who occupied 30 Elizabeth Street. On both occasions the nuisances were abated following the attendance of the City of Melbourne Inspector of Nuisances John Fullerton.